If any of these effects last or get worse, tell your doctor or pharmacist promptly
Find information on Prochlorperazine (Compazine, Compro) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more
In Adult Psychiatric Disorders Adjust dosage
Dosing recommendations for individual drugs can be found in Drug Prescribing in Renal Failure: Dosing Guidelines for Adults
The
What Drugs, Substances, or Supplements Interact with Compazine? Compazine, Compazine Spansules (prochlorperazine) dosing, indications, interactions, adverse effects, and more Lens opacities (with prolonged use) Anticholinergic effects
Dosage forms: -- Brand Discontinued in US [see generic] Contraindications / Cautions
ca Aug 2017 Chronic Kidney Disease Symptom Management Resource
Common Trade Names: Compazine Adult Dosing Headache 10mg IV (slow push or in 1L IVF) Nausea/Vomiting 5-10mg PO or IV q6-8 hours Max: 40mg/day Pediatric Dosing
Prochlorperazine is used to treat nervous, emotional, and mental conditions (eg, schizophrenia) and non-psychotic anxiety
Compazine ® Prochlorperazine Suppositories USP is not approved for the treatment of patients with dementia-related psychosis (see Warnings)
2
5 mg 1 or 2 times a day
For non-psychotic anxiety: Adults—At first, 5 milligrams (mg) 3 or 4 times a day
IM: 5-10 mg administered 1-2 hours before induction of anesthesia; may be repeated once 30 minutes after initial dose IV: 5-10 mg administered 15-30 minutes before induction of anesthesia, repeated once before procedure if desired, or 20 mg/L administered 15-30 minutes before induction; not to exceed 30 mg/day Prochlorperazine is also available under the brand names of Compazine and Compro
• Can interact with certain medications, like antidepressants and migraine medications
It mainly works by depressing the chemoreceptor trigger zone
Allergy to class/drug; Adverse Reactions IM (as mesylate): 5 to 10 mg 2 to 3 times/day; usual maximum: 40 mg/day
There are some simple things you can do on your own that may help your migraine-related nausea: Loosen your clothes, especially around your stomach
Prochlorperazine edisylate is a white to very light yellow powder
Meclizine belongs to a drug class called antihistamines, which are often used to treat allergies
Prochlorperazine Edisylate Injection may be administered either undiluted or diluted in isotonic solution
Prochlorperazine Brand names: Stemetil, Buccastem
Cardiac glycoside
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy (see DOSAGE AND ADMINISTRATION)
The baclofen dose is gradually decreased until the optimal dose is found
ca Aug 2017 Chronic Kidney Disease Symptom Management Resource References 1
Dose Adjustments